師資
研究興趣:
1. 生化分析與分子診斷,；
2. 抗菌新策略及抗菌機(jī)理研究,。
教育背景：
2003-2009,中國(guó)科學(xué)技術(shù)大學(xué), 博士(細(xì)胞生物學(xué))
1999-2003, 湖北師范大學(xué), 學(xué)士(生物科學(xué))
工作經(jīng)歷：
2018-至今，南方科技大學(xué)，研究副教授
2009-2018, 中國(guó)科學(xué)院深圳先進(jìn)技術(shù)研究院, 助理研究員/副研究員
2017–2018, 香港大學(xué), 訪問(wèn)學(xué)者
2006–2007, Morehouse School of Medicine,訪問(wèn)學(xué)者
科研項(xiàng)目：
2017-2020, 蛋白質(zhì)類泛素化修飾的單分子檢測(cè)與成像分析研究,，國(guó)家自然科學(xué)基金面上項(xiàng)目,項(xiàng)目負(fù)責(zé)人
2016-2019, 中國(guó)科學(xué)院青年創(chuàng)新促進(jìn)會(huì)會(huì)員項(xiàng)目,中國(guó)科學(xué)院，項(xiàng)目負(fù)責(zé)人
2011-2013, 動(dòng)點(diǎn)Mis12 復(fù)合物組裝動(dòng)力學(xué)及其在染色體分離中功能解析,國(guó)家自然科學(xué)基金青年科學(xué)基金項(xiàng)目,項(xiàng)目負(fù)責(zé)人
2011-2015, 量子點(diǎn)標(biāo)記技術(shù)研究病毒侵染過(guò)程及宿主應(yīng)答,，國(guó)家重大科學(xué)研究計(jì)劃,項(xiàng)目骨干
獲獎(jiǎng)情況及榮譽(yù)：
深圳市海外高層次人才（孔雀C類）,2018
“廣東特支計(jì)劃”青年拔尖人才,，2017
廣東省科學(xué)技術(shù)獎(jiǎng)二等獎(jiǎng)，2017
中國(guó)科學(xué)院青年創(chuàng)新促進(jìn)會(huì)會(huì)員,，2015
深圳市高層次人才(后備級(jí)),，2014
深圳市自然科學(xué)獎(jiǎng)二等獎(jiǎng)，2014
代表性論文：
[1] Li Y.Y., Yang Y.,* Zhang C.Y.* Visualization and Quantification of Sortase Activity at the Single-Molecule Level via Transpeptidation-Directed Intramolecular F?rster Resonance Energy Transfer. Anal. Chem., 2018, 90, 13007-13012. (Nature Index article, IF=6.042)
[2] Xu A. J., Yang Y.,* Zhang C.Y.* Transpeptidation-directed intramolecular bipartite tetracysteine
display for sortase activity assay. Chem. Commun., 2018, 54, 8116-8119. (Nature Index article, IF=6.29)
[3] Yang Y., Liang Y., Zhang C.Y.* Label-Free and Homogenous Detection of Caspase-3-Like Proteases by Disrupting Homodimerization-Directed Bipartite Tetracysteine Display. Anal. Chem., 2017, 89, 4055-4061. (Nature Index article, IF=6.042)
[4] Zhou J., Yang Y., Zhang C.Y.* Toward Biocompatible Semiconductor Quantum Dots: From Biosynthesis and Bioconjugation to Biomedical Application. Chem. Rev., 2015, 115, 11669-11717. (SCI, IF=52.613).
[5] Wang L. J.,? Yang Y.,? Zhang C.Y.* Phosphorylation-directed assembly of a single quantum dot based nanosensor for protein kinase assay. Anal. Chem., 2015, 87, 4696-4703. (Nature Index article, IF=6.042)
[6] Yang Y., Zhang C.Y.* Visualizing and Quantifying Protein PolySUMOylation at the Single-Molecule Level. Anal. Chem., 2014, 86, 967-972. (Nature Index article, Editors’ Highlight)
[7] Ma F.,? Yang Y.,? Zhang C.Y.* Ultrasensitive Detection of Transcription Factors Using Transcription-Mediated Isothermally Exponential Amplification-Induced Chemiluminescence. Anal. Chem., 2014, 86, 6006-6011. (Nature Index article, IF=6.042)
[8] Yang Y., Zhang C.Y.* Simultaneous measurement of SUMOylation using SNAP/CLIP-tag-mediated translation at the single-molecule level. Angew. Chem. Int. Ed., 2013, 52, 691-694. (Nature Index article, IF=12.102)
[9] Zhou J.,? Yang Y.,? Zhang C.Y.* A low-temperature solid-phase method to synthesize highly
fluorescent carbon nitride dots with tunable emission. Chem. Commun., 2013, 49, 8605-8607. (Nature Index article, Back cover)
[10] Yang Y., Zhang C.Y.* Sensitive Detection of Intracellular Sumoylation via SNAP Tag-Mediated
Translation and RNA Polymerase-Based Amplification. Anal. Chem., 2012, 84, 1229-1234. (Nature
Index article, IF=6.042)
[11] Yang Y., Wu F., Ward T., Yan F., Wu Q., Wang Z.Y., McGlothen T., Peng W., You T. P., Sun M. K., Cui T. X., Hu R. M., Dou Z., Zhu J. D., Xie W., Rao Z. H., Yao X. B.* Phosphorylation of HsMis13 by aurora B is essential for assembly of functional kinetochore. J. Biol. Chem., 2008, 283, 26726-26736.