師資
個(gè)人簡介
傅暘,,南方科技大學(xué)醫(yī)學(xué)院博士生導(dǎo)師,、副教授,、正高級研究員,。課題組綜合利用細(xì)菌遺傳學(xué)、細(xì)菌生理生化,、免疫學(xué),、原位及單顆粒冷凍電鏡等技術(shù),從事病原-宿主-共生菌多元互作,、抗感染技術(shù)和微生物干預(yù)療法研究,。于2013年獲南開大學(xué)生物化學(xué)與分子生物學(xué)博士學(xué)位。自2009年在享譽(yù)世界的哈佛大學(xué)醫(yī)學(xué)院微生物與免疫生物學(xué)系,,師從世界著名微生物學(xué)家,、美國科學(xué)院院士John Mekalanos教授進(jìn)行博士學(xué)習(xí)并繼而從事博士后研究,系統(tǒng)連貫地工作近十年。主要從事病原生物學(xué),、腸道病原-宿主-共生微生物組多元互作,、抗感染治療和新型疫苗研究。多年來通過扎實(shí)的工作積累了豐富經(jīng)驗(yàn),,取得了豐碩成果,。近年來在Cell Host & Microbe、Science Translational Medicine,、P. Natl. Acad. Sci. USA,、Clinical Infectious Diseases、Allergy,、Journal of Immunology,、SCIENCE Bulletin、SCIENCE CHINA Life Sciences和Vaccine等國際權(quán)威學(xué)術(shù)期刊共發(fā)表論文16篇,,第一作者及通訊作者7篇,,均為頂級或1區(qū)期刊,高被引文章4篇,。累計(jì)他引大于2000次,,H-index 9??蒲谐晒粐鴥?nèi)外多個(gè)媒體報(bào)道,,受邀發(fā)表多次重要學(xué)術(shù)會議報(bào)告,,獲Fogarty Global Health Fellowship獎,,擔(dān)任Bio-Protocol雜志編委,mBio等多家知名科學(xué)期刊審稿人,。
學(xué)術(shù)任職
1,、Bio-Protocol雜志編輯
2、Frontiers Cellular and Infection Microbiology??庉?/p>
獲獎榮譽(yù)
1,、國家級人才頭銜
2、深圳市人才頭銜
3,、Fogarty Global Health Fellowship
教育經(jīng)歷
1,、2001.09-2005.06 江南大學(xué),生物工程學(xué)專業(yè)學(xué)士
2,、2006.09-2013.06 南開大學(xué),,生物化學(xué)與分子生物學(xué)專業(yè)博士
3、2009.09-2013.05 哈佛大學(xué),,微生物學(xué)與免疫生物學(xué)專業(yè)聯(lián)培博士
工作經(jīng)歷:
1,、2005.07-2006.08 南開大學(xué),技術(shù)員
2、2008.06-2009.01 哈佛大學(xué)公共衛(wèi)生學(xué)院,,交換生
3,、2013.07-2018.06 哈佛大學(xué)醫(yī)學(xué)院,博士后研究員
4,、2018.07-2019.06 哈佛大學(xué)醫(yī)學(xué)院,,助理研究員
5、2019.06-2020.12 南方科技大學(xué),,助理教授/博士生導(dǎo)師
6,、2021.01-至今 南方科技大學(xué),副教授/博士生導(dǎo)師
代表性論文
Cai, Q., D. Huang, P. Ou, H. Yu, Z. Zhu, Z. Xia, Y. Su, Z. Ma, Y. Zhang, Z. Li, Q. He, L. Liu, Y. Fu# and J. Chen# (2020.03.31). COVID-19 in a designated infectious diseases hospital outside Hubei Province, China. Allergy. (IF: 6.771) # Co-corresponding author
Juanjuan Zhao,Quan Yuan,Haiyan Wang,Wei Liu,Xuejiao Liao, Yingying Su,Xin Wang, Jing Yuan, Tingdong Li,Jinxiu Li,Shen Qian, Congming Hong, Fuxiang Wang, Yingxia Liu, Zhaoqin Wang,Qing He, Zhiyong Li,Bin He, Tianying Zhang,Yang Fu, Shengxiang Ge, Lei Liu, Jun Zhang ,Ningshao Xia, Zheng Zhang(2020.03.28). Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019. Clin Infect Dis. 2020 Mar 28:ciaa344. doi: 10.1093/cid/ciaa344 (IF:9.17)
Juan Xue, Xing Pan, Ting Peng, Meimei Duan , Lijie Du , Xiaohui Zhuang, Xiaobin Cai, Xueying Yi , Yang Fu , Shan Li .(2020.05.05)Auto Arginine-GlcNAcylation Is Crucial for Bacterial Pathogens in Regulating Host Cell Death. Front Cell Infect Microbiol. 2020 May 5;10:197. doi: 10.3389/fcimb.2020.00197
Xuelan Zhou , Fanglin Zhong , Cheng Lin , Xiaohui Hu , Yan Zhang, Bing Xiong , Xiushan Yin , Jinheng Fu , Wei He , Jingjing Duan , Yang Fu , Huan Zhou , Peter J McCormick , Qisheng Wang , Jian Li , Jin Zhang .(2020.9.1)Structure of SARS-CoV-2 main protease in the apo state. Sci China Life Sci. doi: 10.1007/s11427-020-1791-3
Jianghong An, Xuejiao Liao, Tongyang Xiao, Shen Qian, Jing Yuan, Haocheng Ye, Furong Qi, Chengguang Shen, Lifei Wang, Yang Liu, Xiaoya Cheng, Na Li, Qingxian Cai, Fang Wang,Jun Chen, Guojun Li, Qiu’e Cai, Yingxia Liu, Yunfang Wang, Feng Zhang, Yang Fu, Qing He, Xiaohua Tan, Lei Liu, Zheng Zhang. (2020.9.4) Clinical characteristics of the recovered COVID-19 patients with re-detectable positive RNA test. Ann Transl Med 2020;8(17):1084 | http://dx.doi.org/10.21037/atm-20-5602
Jian Li, Xuelan Zhou, Yan Zhang, Fanglin Zhong, Cheng Lin, Peter J.McCormick, Feng Jiang, Jun Luo, Huan Zhou, Qisheng Wang, Yang Fu,Jingjing Duan, Jin Zhang. (2020.9.22) Crystal structure of SARS-CoV-2 main protease in complex with the naturalproduct inhibitor shikonin illuminates a unique binding mode. Science Bulletin https://doi.org/10.1016/j.scib.2020.10.018
Fu Y, Ho BT, & Mekalanos JJ (2018.02.14) Tracking Vibrio cholerae Cell-Cell Interactions during Infection Reveals Bacterial Population Dynamics within Intestinal Microenvironments. Cell host & microbe 23(2):274-281 e272. (IF: 17.87, Ranked 1st in Microbiology, Cell Press Sub-Publication)
Ho BT*, Fu Y*, Dong TG, & Mekalanos JJ (2017.07.17) Vibrio cholerae type 6 secretion system effector trafficking in target bacterial cells. Proceedings of the National Academy of Sciences of the United States of America 114(35):9427-9432. (IF: 9.5, Ranked 3rd in Life Science, Health & Medical Sciences) * Co-First Authors
Fu Y, Waldor MK, & Mekalanos JJ (2013.12.11) Tn-Seq analysis of Vibrio cholerae intestinal colonization reveals a role for T6SS-mediated antibacterial activity in the host. Cell host & microbe 14(6):652-663. (IF: 17.87, Ranked 1st in Microbiology, Cell Press Sub-Publication, Cited By 125)
Fu Y# & Mekalanos JJ# (2014.06.05) Infant Rabbit Colonization Competition Assays. Bio Protoc 4(11). # Co-Corresponding Authors
Altindis E, Fu Y, & Mekalanos JJ (2014.02.28) Proteomic analysis of Vibrio cholerae outer membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America 111(15): E1548-1556. (IF: 9.5, Ranked 3rd in Life Science, Health & Medical Sciences [general], Cited by 74)
Sanchez-Larrayoz AF, Elhosseiny, NM, Chevrette MG, Fu Y, Giunta P, Spallanzani RG, Ravi K, Pier GB, Lory S, and Maira-Litran T (2017.08.30) Complexity of Complement Resistance Factors Expressed by Acinetobacter baumannii Needed for Survival in Human Serum. J Immunol 199, 2803-2814. (IF: 4.54, Ranked 6th in Immunology)
Roux, D, Danilchanka, O, Guillard, T, Cattoir, V, Aschard, H, Fu, Y, Angoulvant, F, Messika, J, Ricard, JD, Mekalanos, JJ, et al. (2015.07.22). Fitness cost of antibiotic susceptibility during bacterial infection. Sci Transl Med 7, 297ra114. (IF: 16.71, Ranked 10th in Health & Medical Sciences [general], Science Sub-Publication, Cited By 63)
Liao Q, Strong A. J, Liu Y, Meng P, Fu Y, Touzjian N, Shao Y, Zhao Z, Lu Y (2012.01.17) HIV vaccine candidates generate in vitro T cell response to putative epitopes in Chinese-origin rhesus macaques. Vaccine. 30(9): 1601-1608. (IF: 3.3, Ranked 3rd in Virology)
Xiangke Duan, Yang Fu, and Liang Yang. Chapter 5Molecular and Systems Biology Approaches for Analyzing Drug-Tolerant Bacterial Persister Cells https://doi.org/10.1007/978-3-030-53024-2_5